Welcome to Xi an Jiaotong University School of Materials Science and Engineering

Associate Professor
Li Bo
中文姓名 李博

Email: libo1137@xjtu.edu.cn

Webpage: https://gr.xjtu.edu.cn/en/web/libo1137

Research interests:

1.  Bio-functional coatings design and fabrication on biometals, including Mg, Ti et al.

2.  Biological effects evaluation and the molecular biological mechanisms investigation of the bio-functional coatings

Experience:

2019.07 – Present   Xi'an Jiaotong University, China   Associate professor

2016.03 – 2019.07   Xi'an Jiaotong University, China    Lecturer  

2016.03 – Present   Xi'an Jiaotong University, China   Postdoc  

Education:

2009.06 – 2016.03   Xi'an Jiaotong University, China   Ph.D.

2005.09 – 2009.06   Xi’an University of technology    B.Sc.

Honor & Awards:

2019  Honor for Excellent Doctoral Thesis of Shaanxi Province,

2018  Honor for Excellent Doctoral Thesis of Xi'an Jiaotong University

Representative Publications:


1)        D.M. Yu#, S. Guo#, M. Yu#, W.W. Liu, X.K. Li, D.F. Chen, B. Li**, Z. Guo***, Y. Han*. Immunomodulation and osseointegration activities of Na2TiO3 nanorods-arrayed coatings doped with different Sr content. Bioactive Materials 10 (2022) 323-334

2)        J. Ye#, B. Li#**, M. Li, Y.F. Zheng, S.L. Wu, Y. Han*. Formation of a ZnO nanorods-patterned coating with strong bactericidal capability and quantitative evaluation of the contribution of nanorods-derived puncture and ROS-derived killing. Bioactive Materials 11 (2022) 181-191

3)        J. Ye#, B. Li#, M. Li, Y.F. Zheng, S.L. Wu, D.F. Chen, Y. Han*. Eco-friendly bacteria-killing by nanorods through mechano-puncture with top selectivity. Bioactive Materials 15 (2022) 173-184

4)        R. Huang, L. Liu, B. Li, L. Qin, L. Huang, K.W.K. Yeung*, Y. Han*. Nanograins on Ti-25Nb-3Mo-2Sn-3Zr alloy facilitate fabricating biological surface through dual-ion implantation to concurrently modulate the osteogenic functions of mesenchymal stem cells and kill bacteria. Journal of Materials Science & Technology 73 (2021) 31-44

5)        D.M. Yu#, S. Guo#, D. Yang#, B. Li*, Z. Guo*, Y. Han*. Interrod spacing dependent angiogenesis and osseointegration of Na2TiO3 nanorods-patterned arrays via immunoregulation. Chemical Engineering Journal 426 (2021) 131187

6)        H.W. Yang#, M. Yu#, R. Wang, B. Li, X. Zhao, Y.L. Hao, Z. Guo, Y. Han*. Hydrothermally grown TiO2-nanorods on surface mechanical attrition treated Ti: Improved corrosion fatigue and osteogenesis. Acta Biomaterialia 116 (2020) 400-414

7)        J. Ye#, B. Li#, M. Li, Y.F. Zheng, S.L. Wu, Y. Han*. ROS induced bactericidal activity of amorphous Zn-doped titanium oxide coatings and enhanced osseointegration in bacteria-infected rat tibias. Acta Biomaterialia 107 (2020) 313-324

8)        B. Li#, R. Huang#, J. Ye#, L. Liu, L. Qin, J.H. Zhou, Y.F. Zheng, S.L. Wu, Y. Han*. A self-healing coating containing curcumin for osteoimmunomodulation to ameliorate osseointegration. Chemical Engineering Journal 403 (2020) 126323

9)        D.L. Han, Y. Li, X.M. Liu*, B. Li, Y. Han, Y.F. Zheng, K.W.K. Yeung, C.Y. Li, Z.D. Cui, Y.Q. Liang, Z.Y. Li, S.L. Zhu, X.B. Wang, S.L. Wu*, Rapid bacteria trapping and killing of metal-organic frameworks strengthened photo-responsive hydrogel for rapid tissue repair of bacterial infected wounds. Chemical Engineering Journal 396 (2020) 125194

10)     Y.Q. Qiao, X.M. Liu*, B. Li, Y. Han, Y.F. Zheng, K.W.K. Yeung, C.Y. Li, Z.D. Cui, Y.Q. Liang, Z.Y. Li, S.L. Zhu, X.B. Wang, S.L. Wu*. Treatment of MRSA-infected osteomyelitis using bacterial capturing, magnetically targeted composites with microwave-assisted bacterial killing. Nature Communications 11 (2020) 4446

11)     Y. Li, X.M. Xu, X.M. Liu*, B. Li, Y. Han, Y.F. Zheng, D.F. Chen, K.W.K. Yeung, Z.D. Cui, Z.Y. Li, Y.Q. Liang, S.L. Zhu, X.B. Wang, S.L. Wu*. Photoelectrons mediating angiogenesis and immunotherapy through heterojunction film for noninvasive disinfection. Advanced Science 7 (2020) 2000023

12)     L. Tan#, J.N. Fu#, F. Feng#, X.M. Liu, Z.D. Cui, B. Li, Y. Han, Y.F. Zheng, K.W.K. Yeung, Z.Y. Li, S.L. Zhu, Y.Q. Liang, X.B. Feng, X.B. Wang, S.L. Wu*. Engineered probiotics biofilm enhances osseointegration via immunoregulation and anti-infection. Science Advances 6 (2020) eaba5723

13)     Bo Li, Peng Gao, Haoqiang Zhang, Zheng Guo, Yufeng Zheng, Yong Han*, Osteoimmunomodulation, osseointegration, and in vivo mechanical integrity of pure Mg coated with HA nanorod/pore-sealed MgO bilayer, Biomaterials Science, 2018, 6(12): 3202-3218

14)    Bo Li, Yong Han *, Mei Li. Enhanced osteoblast differentiation and osseointegration of bio-inspired HA nanorod patterned pore-sealed MgO bilayer coating on magnesium, Journal of materials chemistry B, 2016, 4: 683-693

15)    Bo Li, Yong Han *, Kai Qi. Formation mechanism, degradation behavior, and cytocompatibility of a nanorod-shaped HA and pore-sealed MgO belayer coating on magnesium, ACS applied materials & interfaces, 2014, 6: 18258-18274

16)    Bo Li, Yong Han *. Fast formation of a novel bilayer coating with enhanced corrosion resistance andcytocompatibility on magnesium, RSC Advances, 2015, 5: 46109-46118

17)    Jianghong Zhou#, Lingzhou Zhao#Bo Li, Yong Han*, Nanorod diameter modulated osteogenic activity of hierarchical micropore/nanorod-patterned coatings via a Wnt/β-catenin pathway, Nanomedicine: Nanotechnology, Biology, and Medicine, 2018, 14(5): 1719-1731

18)    6.  Jianhong Zhou, Bo Li, Yong Han*, F-doped TiO2 microporous coating on titanium with enhanced antibacterial and osteogenic activities, Scientific Reports, 2018, 8: 17858

19)    Wei Yuan, Bo Li, Dafu Chen*, Donghui Zhu, Yong Han*, Yufeng Zheng*, Formation Mechanism, Corrosion Behavior, and Cytocompatibility of Microarc Oxidation Coating on Absorbable High-Purity Zinc, ACS Biomater. Sci. Eng. 2019, 52: 487-497

20)    Jianhong Zhou, Bo Li, Lingzhou Zhao, Lan Zhang, Yong Han*, F-Doped Micropore/Nanorod Hierarchically Patterned Coatings for Improving Antibacterial and Osteogenic Activities of Bone Implants in Bacteria-Infected Cases, ACS biomaterials science & engineering, accepted, DOI: 10.1021/acsbiomaterials.6b00710

21)    Jianhong Zhou, Bo Li, Yong Han*, Lingzhou Zhao*, The Osteogenic Capacity of Biomimetic Hierarchical Micropore/nanorod-patterned Sr-HA Coatings with Different Interrod Spacings, Nanomedicine: Nanotechnology, Biology, and Medicine, 2016, 12(5): 1161-1173

22)    Jianhong Zhou, Bo Li, Shemin Lu, Lan Zhang, Yong Han*, Regulation of Osteoblast Proliferation and Differentiation by Interrod Spacing of Sr-HA Nanorods on Microporous Titania Coatings, ACS applied materials & interfaces, 2013, 5(11): 5358-5365


Patents:

1.  Bo Li, Liang Qin, Yong Han, A bioactive coating with self-healing property formed on Mg substrate, ZL 201910217929.2

2.  Yong Han, Bo Li, Preparation of a bilayer coating consisted sealed MgO and hydroxyapatite nanofiber on Mg substrate, ZL 201210166536.1

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